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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC1
All Species:
21.21
Human Site:
T249
Identified Species:
42.42
UniProt:
P33527
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33527
NP_004987.2
1531
171561
T249
W
S
L
N
K
E
D
T
S
E
Q
V
V
P
V
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
T43
G
R
P
H
N
G
F
T
S
L
C
S
K
Q
P
Rhesus Macaque
Macaca mulatta
XP_001094709
1612
178491
R334
W
S
L
K
E
E
D
R
S
Q
M
V
V
Q
Q
Dog
Lupus familis
XP_548204
1523
168842
V248
D
D
C
S
Q
K
V
V
N
R
L
L
E
A
W
Cat
Felis silvestris
Mouse
Mus musculus
O35379
1528
171166
T249
W
S
L
N
K
E
D
T
S
E
E
V
V
P
V
Rat
Rattus norvegicus
Q8CG09
1532
171475
T249
W
S
L
N
K
E
D
T
S
E
E
V
V
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
T261
W
S
L
N
R
E
D
T
S
D
Q
V
V
P
V
Chicken
Gallus gallus
Q5F364
1525
170953
T249
W
S
L
N
K
E
D
T
S
E
E
I
V
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
K249
W
S
L
N
N
E
D
K
S
E
R
V
V
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995704
1548
173512
E253
K
G
Y
R
N
P
L
E
E
K
D
L
W
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42093
1623
182111
L248
W
M
N
P
L
M
T
L
G
S
K
R
P
L
T
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
S251
Y
K
L
P
R
N
F
S
S
E
E
L
S
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
54.1
56.6
N.A.
88.1
87.4
N.A.
84.2
77.6
N.A.
70.5
N.A.
51.2
N.A.
N.A.
N.A.
Protein Similarity:
100
80.1
71
74.1
N.A.
94.7
93.8
N.A.
91.7
89.2
N.A.
83.2
N.A.
68.5
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
53.3
0
N.A.
93.3
93.3
N.A.
86.6
80
N.A.
73.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
66.6
33.3
N.A.
100
100
N.A.
100
93.3
N.A.
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.2
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.8
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
59
0
0
9
9
0
0
9
0
% D
% Glu:
0
0
0
0
9
59
0
9
9
50
34
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
9
0
0
9
0
0
0
0
0
9
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
9
9
0
9
34
9
0
9
0
9
9
0
9
0
9
% K
% Leu:
0
0
67
0
9
0
9
9
0
9
9
25
0
9
9
% L
% Met:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
50
25
9
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
9
17
0
9
0
0
0
0
0
0
9
50
9
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
17
0
0
25
17
% Q
% Arg:
0
9
0
9
17
0
0
9
0
9
9
9
0
0
0
% R
% Ser:
0
59
0
9
0
0
0
9
75
9
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
9
50
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
9
9
0
0
0
50
59
0
34
% V
% Trp:
67
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _